Medial Prefrontal Cortex Modulation of the Peripheral Immune Response in Sepsis Via the Autonomic Nervous System.
BACKGROUND Sepsis is a life-threatening organ dysfunction syndrome caused by a dysregulated host response to infection, in which neuroimmune dysfunction plays a central role. The medial prefrontal cortex (mPFC) is involved in autonomic and immune regulation. However, its role in modulating peripheral immune responses d...