CD300f negatively regulates microglial pyroptosis via the JAK2/STAT3 axis in sepsis-associated encephalopathy.
Sepsis-associated encephalopathy (SAE) is a multifactorial medical condition characterized by pronounced neuroinflammation and linked to increased mortality risk and long-term cognitive impairment. Microglial pyroptosis has emerged as a crucial pathogenic mechanism in SAE. CD300f, an immune receptor expressed in microg...