Shi-Huan Yin

Hyperperins A-X, fusicoccane diterpenoids including an unreported 5/7/5/3 tetracyclic carbon skeleton from Hypoestes purpurea and their T-type calcium channel inhibitory activity.

Two unprecedented rearranged fusicoccane diterpenoids, hyperperins A (1) and B (2), and twenty-two new fusicoccane diterpenoids, hyperperins C-X (3-24), were isolated from the aerial parts of Hypoestes purpurea, as well as one known analog (25). The structures and absolute configurations of all newly isolated compounds...