Author

Shijie Chen

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Open access Aug 2026

Blocking the m6Am methyltransferase PCIF1 in macrophages attenuates colitis progression by preventing neuronal damage

Chen-Bo Ding, Jia-Cheng Zhao, Tian-Hua Zhao et al. · Cellular & Molecular Immunol... · 0 citations

Open access Jul 2026

Blocking the m6Am methyltransferase PCIF1 releases STAT1-mediated Th1 immunity to potentiate cancer immunotherapy

It is shown, by genomic deletion of PCIF1 specifically in T cells, that PCIF1 represses STAT1 translation via this important mRNA modification, and thereby preventing T cell activation and enforcing a naïve T cell phenotype.

Jian-Song Huang, Jing Zhou, Xiao Liu et al. · Nature Communications · 1 citation