Candidate Right Locus Coeruleus‐Centered Symptom Pathways in Young Major Depressive Disorder: A Multimodal Magnetic Resonance Imaging Study
Major depressive disorder (MDD) involves network‐level abnormalities that may reflect dysfunction in catecholaminergic nuclei, particularly the substantia nigra (SN) and locus coeruleus (LC), which regulate cortical gain and signal‐to‐noise ratio. However, whether MRI‐derived SN/LC phenotypes are linked to depressive s...