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Shi-Jun Qiu

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Open access Aug 2026

Candidate Right Locus Coeruleus‐Centered Symptom Pathways in Young Major Depressive Disorder: A Multimodal Magnetic Resonance Imaging Study

Major depressive disorder (MDD) involves network‐level abnormalities that may reflect dysfunction in catecholaminergic nuclei, particularly the substantia nigra (SN) and locus coeruleus (LC), which regulate cortical gain and signal‐to‐noise ratio. However, whether MRI‐derived SN/LC phenotypes are linked to depressive s...

Ze-Song Yuan, Jing Wang, Danian Li et al. · 0 citations
Open access Aug 2026

Normative modelling of cortical networks identifies subtypes of type 2 diabetes associated with distinct clinical and transcriptomic profiles

Type 2 diabetes (T2D) is characterized by substantial clinical heterogeneity, yet its neurobiological substrates remain unclear. Here, we leverage normative modelling of cortical morphometric networks to quantify individual-level brain deviations using structural MRI data from 3,723 participants (1,941 T2D patients and...

Xiaoyue Wang, Zhizhong Sun, Jian-Cheng Cao et al. · 0 citations

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