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Author

Shimin Dong

2 papers indexed here

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Open access Oct 2026

FOXA1-driven transcription and TRIM9-mediated ubiquitination of LCN2 modulate ferroptosis in experimental sepsis-induced acute lung injury

Sepsis-induced acute lung injury (ALI) remains a devastating complication of sepsis, marked by uncontrolled pulmonary inflammation, alveolar-capillary barrier disruption, and high mortality. Ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxidation, is implicated in sepsis-related org...

Jin Li, Ya-Zhou Li, Chun-Tao Song et al. · 0 citations
Aug 2026

Isoquercitrin alleviates sepsis-induced myocardial injury via the EGFR/PI3K/AKT signaling pathway.

BACKGROUND Sepsis-induced myocardial injury is a life-threatening complication. Isoquercitrin (IQC), a natural flavonoid glycoside, exhibits anti-inflammatory and anti-apoptotic properties, yet its role in septic cardiomyopathy remains unclear. METHODS IQC targets were predicted via transcriptomics and molecular dock...

Hexin Zhai, Xingwei Yang, Yan Shao et al. · 0 citations

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