Author

Shi-ping Xian

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Jul 2026

The epigenetic KMT5C-HDAC1 axis promotes hepatocellular carcinoma stemness and progression through SERPINA4 repression and chromatin compaction

This work establishes the KMT5C-HDAC1 axis as a central epigenetic switch that governs HCC stemness and progression, revealing a co-targeting strategy for the treatment of aggressive HCC.

Hong-Bin Huang, Cainian Huang, Pangfei Yang et al. · Oncogene · 0 citations