Shi-Qian Huang

Polyamine metabolism in ischemia reperfusion injury: common mitochondrial mechanisms and organ-specific differences

Polyamines are essential polycations that play pivotal roles in various cellular processes, including cell proliferation, redox regulation, protein synthesis, and particularly the maintenance of mitochondrial function. During ischemia/reperfusion injury (I/RI), mitochondrial dysfunction emerges as a common mechanism un...