Shi-Rong Yi

Targeted reprogramming of macrophages by inhalable dual-ligand-engineered liposomes via mechano-biochemical signaling coupling to improve acute lung injury.

It is demonstrated that engineered liposomes with optimization of their surface ligands and mechanical properties can effectively achieve targeted reprogramming of inflammatory macrophages, and provides a promising drug-free, inhalable nanotherapeutic platform for ALI treatment.