Open access
Sep 2026
Ent-abietane diterpenoid Enantiomers from Euphorbia helioscopia inhibits liver fibrosis via suppressing the TGF-β1/smad pathway
Mechanistic investigations revealed that the anti-fibrotic action of 1b in hepatic cells is probably mediated through the TGF-β/Smad signaling cascade, and position abietane-type diterpenoids as prospective molecular structures for the innovation of new therapeutics against liver fibrosis.
Li Jiang, Qian Wang, Jun-Yan Ran et al.
· Arabian Journal of Chemistry · 0 citations