Aberrant phase separation from a rare ABI3 mutation drives microglial dysfunction and Alzheimer's risk
Although the ABI3 S209F variant is a recognized genetic risk for Alzheimer's disease (AD), its pathogenic mechanism remains elusive.
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Although the ABI3 S209F variant is a recognized genetic risk for Alzheimer's disease (AD), its pathogenic mechanism remains elusive.
The shared genetic architecture between rheumatoid arthritis and psychiatric disorders is elucidated, providing novel insights into the pathological mechanisms underlying their comorbidity and laying groundwork for improved comorbidity management.
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