Open access
Sep 2026
LGALS3 marks a pro-inflammatory, efferocytosis-low hepatic macrophage state and promotes hepatic stellate cell activation through the candidate receptor ANXA2 in liver cirrhosis.
Introduction Efferocytosis is a macrophage-dependent process responsible for clearing apoptotic cells. Reduced efferocytic capacity may be one of the factors contributing to liver cirrhosis (LC). This research aimed to identify and validate efferocytosis-related genes (EFRGs) associated with LC and investigate their po...
Feng-Chun Li, Hong-Liang Chen, Ji-Han Qi et al.
· Frontiers in Immunology · 0 citations