Engineering a Disulfide-Directed Hairpin-Shaped Antifouling Peptide for Reliable Electrochemical Detection of CA15-3 in Human Serum.
The precise detection of biomarkers in complex biofluids remains a significant challenge for electrochemical biosensors, largely due to the nonspecific adsorption of proteins and other molecules. While zwitterionic peptides offer excellent antifouling properties, their typical linear architectures are prone to protease...