Oct 2026
ESCAPE enables receptor-specific chemogenetic dissection of GPCR signaling.
G-protein-coupled receptors (GPCRs) are essential mediators of cellular processes, and their dysfunction is implicated in various diseases. Although pharmacological approaches are powerful for elucidating GPCR functions, careful consideration of potential off-target effects remains crucial. Here, we present an off-targ...
Yuma Matsuoka, Hajime Inoue, Tatsuki Hori et al.
· Cell Chemical Biology · 0 citations