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Author

Shimon Amir

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Open access Oct 2026

Dorsomedial striatal Bmal1 deletion in medium spiny neurons alters EPSCs and dendritic morphology after chronic exposure to alcohol in female mice

Circadian clock genes in the striatum modulate alcohol drinking behavior in female mice, but the underlying synaptic mechanisms remain unknown. Medium spiny neurons (MSNs) of the striatum express D1- or D2-type dopamine receptors, which are differentially modulated by alcohol. Here we used whole-cell patch-clamp record...

Mahgol Darvishmolla, Richard Courtemanche, Shimon Amir et al. · 0 citations
Open access Aug 2026

Region-specific Bmal1 deletion in the dorsal striatum alters alcohol consumption in a sex-specific manner

Background Circadian disruption is strongly associated with alcohol use disorder (AUD), but insight into the underlying brain-region and sex-specific mechanisms is limited. The function of the circadian clock gene Bmal1 within the striatum has been linked to alcohol drinking, yet its role within functionally distinct s...

Mahgol Darvishmolla, Richard Courtemanche, Shimon Amir · 0 citations

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