Shin-Wha Lee

Paired Transcriptomic Profiling Identifies Shared Liver Metastasis-Associated Molecular Features in Colorectal Cancer

Colorectal cancer liver metastasis (CCLM) is closely associated with poor patient prognosis, yet patient-specific molecular heterogeneity complicates the identification of recurrent molecular changes during metastasis. To address this, we performed RNA sequencing on paired primary tumors and liver metastases synchronou...