Shinichiro Takahashi

Mini-review metallothioneins as redox-adaptive regulators of ferroptosis and therapy resistance in cancer: a mini review

Abstract Ferroptosis is an iron-dependent form of regulated cell death characterized by lipid peroxidation and has emerged as a promising therapeutic target in cancer. However, increasing evidence indicates that tumor cells develop adaptive mechanisms to evade ferroptosis, limiting the efficacy of ferroptosis-inducing...