Author

Shinji Shimoda

2 papers indexed here

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Open access Aug 2026

Enhanced liver injury and fibrosis markers after anti-PD-1 treatment in an HFD/CCl4-accelerated MASH-fibrosis mouse model

It is suggested that PD-1 blockade may provoke unintended pathological consequences in the context of chronic metabolic liver injury in the context of non-neoplastic MASH environment.

Panuwat Promsorn, Takashi Yamaguchi, Eriko Yamamoto et al. · Scientific Reports · 0 citations

Aug 2026

rs57494551 increases CXCR5 expression and IgM+ CXCR5+ B-cell infiltration in the portal area of primary biliary cholangitis.

Immune dysregulation and portal inflammation are affected by increased expression of CXCR5 on IgM+ B-cells in PBC patients who have the risk allele of rs57494551, indicating that CXCR5 is a potential therapeutic target for PBC.

Hitomi Yuki, Yoshihiro Aiba, Kazuko Ueno et al. · Journal of gastroenterology · 0 citations