Open access
Sep 2026
A transcription factor regulatory atlas for activity inference and perturbation prediction
Abstract Inferring transcription factor (TF) activity from transcriptomes and predicting transcriptome-wide responses to TF perturbations remain challenging, in part because available TF–mRNA resources often face a trade-off between precision and coverage and typically lack signed regulatory information. Here, we prese...
Hikaru Sugimoto, Koki Tsuyuzaki, Zhao-Nan Zou et al.
· Nucleic Acids Research · 0 citations