Selective photodegradation of G-quadruplex DNA by a cationic zinc phthalocyanine: role of binding geometry.
The selective photodegradation of G-quadruplex DNA (GQ) was investigated using the cationic zinc phthalocyanine ZnPc as a photosensitizer. UV-Vis absorption titration suggests that electrostatic interactions contribute to ZnPc association with both duplex and G-quadruplex DNA, whereas 1H NMR analysis indicates that one...