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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Shiqi Jiang

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2 papers indexed here

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Open access Sep 2026

Development and Validation of a UPLC–MS/MS Method for Simultaneous Quantification of Ensartinib and Its Major Metabolite M465 in Rat Plasma and Application to Pharmacokinetic Studies

A sensitive, reliable, and rapid UPLC–MS/MS method was developed and validated for the simultaneous determination of ensartinib and M465 in rat plasma and applied to a rat pharmacokinetic study and provides useful analytical support for further preclinical investigations of ensartinib and its major metabolite.

Shi-Qi Jiang, Yan Chen, Lu Cao et al. · 0 citations
Aug 2026

Simultaneous determination of bosutinib and its metabolite in rat plasma by UPLC-MS/MS: Development, validation and application to pharmacokinetic and metabolic stability studies.

In vivo pharmacokinetic studies confirmed that the UPLC-MS/MS method could be successfully used for the analysis of bosutinib after oral administration of 50 mg/kg in rats, and provides a potential reference for the clinical investigation of bosutinib.

Pei-Qi Wang, Yan Chen, Jun Wu et al. · 0 citations

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