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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Shiqi Xie

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Open access Jul 2026

Joint analysis of multiply perturbed cells improves statistical power and cost efficiency in Perturb-seq

Overall, this work recommends a design that intentionally includes single-guide cells, guide doublets, and guide triplets to improve cost efficiency while preserving signal recovery, and develops PerturbMatch, a scalable statistical framework to analyze guide multiplets.

Jake Yeung, Jenille Tan, Liang Wang et al. · 0 citations

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