Author

Shivank Sharma

3 papers indexed here

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Sep 2026

Oxadiazole-based Inhibitors Targeting Carbohydrate-Hydrolyzing Enzymes in Type 2 Diabetes Mellitus: Synthetic Strategies, Structure- Activity Relationships, and Translational Perspectives.

Type 2 diabetes mellitus (T2DM) is a multifactorial metabolic disorder characterized by insulin resistance, progressive β-cell dysfunction, and chronic hyperglycemia, leading to microvascular and macrovascular complications. Among current therapeutic strategies, inhibition of intestinal carbohydrate-hydrolyzing enzymes...

Shivank Sharma, Shubham Kumar, Pankaj Wadhwa · Mini-Reviews in Medical Chem... · 0 citations

Sep 2026

Structure-based Drug Design and Pharmacokinetic Profiling of Novel Heterocyclic Androgen Receptor Inhibitors for Prostate Cancer Treatment

Prostate cancer is one of the most prevalent malignancies and the second leading cause of cancer-related death in men after cardiovascular diseases. Currently available therapies, such as bicalutamide, suffer from limitations, including off-target effects and resistance, highlighting the urgent need for novel andro...

Vanktesh Kumar, Shivank Sharma, Saminesh Kumar et al. · Current Organocatalysis · 0 citations

Review Open access Aug 2026

Unveiling the fate, function, and bioimpact of oxidized antioxidant derivatives in food systems

Antioxidants are traditionally recognized for their ability to neutralize reactive oxygen species and prevent oxidative deterioration in food systems. However, their biological and technological significance extends beyond radical scavenging, as they undergo oxidation to form reactive derivatives that may exert both be...

Shivank Sharma, Vanktesh Kumar · Discover Chemistry · 0 citations