Open access
Sep 2026
Postnatal Ketone Deficiency Impairs Adult Oocyte Quality via Enhancing Histone Acetylation in Malnourished Mice.
Early postnatal life is important for reproductive development, but the effects of early-life nutrition on female reproductive capacity remain largely unknown. Here, we investigated whether neonatal ketone body deficiency affects adult oocyte quality using a lactational malnutrition model and Hmgcs2-deficient mice. We...
Xin-Ge Zhang, Ming-Zhi Li, Han Sha et al.
· Journal of Biological Chemis... · 0 citations