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Shiyu Feng

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Preprint Jul 2026

RareLens: Towards End-to-End Rare Disease Care via Aligning Divergent Large Language Model Reasoning

Autonomous RareLens and physicians assisted by RareLens both outperformed unaided physicians, while demonstrating that effective human-AI collaboration requires more than simply providing model outputs, and suggest a general strategy for building AI systems that operate reliably under high clinical uncertainty.

Xi Chen, Hongru Zhou, Shiyu Feng et al. · 0 citations