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Author

Shiyu Sun

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Aug 2026

Vesicle Nucleating peptide 6 (VNp6) mediates efficient soluble expression of recombinant proteins in Escherichia coli.

Escherichia coli is a dominant host for recombinant protein production due to its well-characterized genetics and low cultivation cost, yet high-level intracellular expression frequently leads to insoluble inclusion bodies. Targeting proteins to the periplasm represents an effective strategy for improving soluble expre...

Jing-Xin Luo, Bin-Bin Wang, Gui-Fang Tian et al. · 1 citation
Open access Jul 2026

Mucosal boosting of chimpanzee adenovirus-vectored vaccine encoding SARS-CoV-2 RBD-heterodimer provides robust protection in mice

A chimpanzee adenovirus (AdC68)-vectored vaccine expressing the Delta-XBB receptor-binding domain (RBD)-dimer is constructed and comprehensively compared the immune responses induced by intramuscular injection, intranasal administration, or aerosol inhalation, revealing that aerosol inhalation provided significantly be...

Xue-Yuan Liu, Yaling An, Huixin Duan et al. · 0 citations

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