Shobit Garg

Mania in genetically confirmed Wieacker–Wolff syndrome with congenital vertical talus: expanding the neuropsychiatric spectrum of ZC4H2-associated disorder

Wieacker–Wolff syndrome (WWS), also termed ZC4H2-associated rare disorder (ZARD), is a rare X-linked neurodevelopmental disorder caused by pathogenic variants in ZC4H2 at chromosome Xq11.2. Core manifestations include developmental delay, hypotonia, intellectual disability, distal muscle weakness and congenital contrac...