Author

Shoichi Suenaga

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Open access Sep 2026

STING activation drives pericentrosomal positioning of acidic organelles via the VAIL-LRRK2-Rab35 pathway

It is found that STING activation in microglia induces the translocation of LRRK2 to the pericentrosomal area, where lysosomes and recycling endosomes (REs) concentrate, and LRRK2 was found to be localized to the organelles.

Shoichi Suenaga, Maria Sakurai, T. Iwatsubo et al. · bioRxiv · 0 citations