Type 2 diabetes is a common chronic condition requiring continuous management. Without a healthy lifestyle and regular treatment, it can lead to severe complications that greatly reduce the patients’ quality of life. Although support for medication management is well-studied and recommended in clinical guidelines...
K. Ueda, H. Okada, Shota Suzuki· BMC Public Health· 0 citations
Although randomized controlled trials have demonstrated the efficacy of real-time continuous glucose monitoring (rtCGM), evidence from routine clinical practice remains limited, particularly in Asian populations. This study aimed to evaluate the effectiveness and safety of rtCGM initiation in individuals with diabetes....
Masao Toyoda, N. Sakane, A. Suganuma et al.· Endocrine journal· 0 citations
l-lysine 6-dehydrogenase (LysDH; EC 1.4.1.18) oxidatively deaminates the ε-amino group of l-lysine. Due to its high substrate specificity, LysDH serves as a valuable tool for l-lysine quantification. However, the molecular basis of this specificity has remained unclear because of the lack of substrate-bound structures....
Toshiya Funahashi, H. Yamaguchi, Shota Suzuki et al.· Journal of Structural Biolog...· 0 citations
GPR84 is an orphan class A GPCR primarily expressed in immune cells, where it plays key roles in inflammation and metabolism. Here, we present the cryo-electron microscopy structures of the GPR84-Gi complex bound to the G protein–biased agonist DL-175, and the inactive state of GPR84 bound to the antagonist GLPG1205. C...
Shota Suzuki, D. Tran, Kouki Nishikawa et al.· Nature Communications· 0 citations
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