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Author

Shrijana Shrestha

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Open access Sep 2026

Persistence of immune responses 5 years after vaccination with a single dose of typhoid conjugate vaccine (TCV) in Nepalese children.

BACKGROUND A single-dose typhoid conjugate vaccine (TCV) has been recommended in endemic settings. Here we report the 5-year immunogenicity results post a single dose of TCV in Nepal. METHODS We conducted a participant- and observer-blinded randomised trial (RCT) in Lalitpur, Nepal (2017-2021) (ISRCTN43385161). 20,01...

D. Pant, Yi-Yuan Zhang, Francesca Feaheny et al. · 0 citations
Review Open access Aug 2026

8-year vaccine protection following a single dose of Vi-tetanus toxoid conjugate vaccine in children in Nepal (TyVOID): a prospective cohort follow-up study of the TyVAC Nepal randomised controlled trial.

BACKGROUND In low-income and middle-income countries, where typhoid fever remains a major public health problem, WHO recommends the use of typhoid conjugate vaccine (TCV). Here, we report vaccine effectiveness up to 8 years following a single dose of TCV in Nepal. METHODS TyVOID was a prospective cohort study that ex...

D. Pant, Yi-Yuan Zhang, F. W. Basile et al. · 1 citation

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