Open access
Oct 2026
High-throughput identification of chromatin-opening transcription factors
The capacity of a newly expressed TF to open chromatin strongly depends on the cell type, cell state and gene regulatory network it lands in, and charting these dependencies will inform how cell fate transitions are initiated in development, homeostasis and disease, and how to engineer them in silico, in vitro and in v...
Aidan Keith, Shruti Jain, R. Daza et al.
· bioRxiv · 0 citations