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Shu-Fang He

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Open access Sep 2026

ZC3HAV1 promotes osteosarcoma metastasis through TSC1 mRNA destabilization and mTORC1 pathway activation

Pulmonary metastasis is the leading cause of mortality in osteosarcoma patients, yet the molecular mechanisms that sustain invasive malignancy within metastatic niches remain poorly understood. Through analysis of single-cell transcriptomic data from osteosarcoma lung metastases and clinical survival datasets, this s...

Jia-Min Zhang, Jia-Hui Guo, Xun-Rui Chen et al. · 0 citations

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