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Shu-Hao Xu

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Open access Sep 2026

The expressions and m6A methylation modification patterns of mRNAs and lncRNAs in major depressive disorder

Objective To systematically characterize the epitranscriptomic landscape of N6-methyladenosine (m6A) methylation in major depressive disorder (MDD) and elucidate its functional consequences on mRNA and lncRNA regulation. Methods We performed comprehensive m6A methylome profiling using microarray analysis of peripheral...

Liang Liu, Zhao-Nan Yang, K. Tan et al. · Frontiers in Genetics · 0 citations

Open access Aug 2026

ARID5A RNA-binding coordinates microglial defense and ferroptosis in iPSC-derived models

It is shown that ARID5A regulates RNA processing in microglia, linking immune and lysosomal pathways to iron-driven death in neurodegeneration and highlighting the importance of protein-RNA interactions in regulating microglial cell biology.

Danielle M. Schafer, Steven M. Blue, Shu-Hao Xu et al. · Nature Communications · 0 citations