Persistent infection with high-risk human papillomavirus (HPV) types 16 and 18 is the primary cause of cervical cancer, and vaccination is an effective prevention method. The assessment of vaccine efficacy relies on measuring neutralizing antibodies (nAbs). However, the pseudovirion-based neutralization assay (PBNA), w...
Lin-Lin Wang, Wei-Ya Mao, Zhuo Zhang et al.· Journal of Virological Metho...· 0 citations
A stratified strategy for HPV16- and HPV18-specific immune monitoring using PBNA as a functional laboratory reference, cCLIA for high-throughput surrogate assessment, and IgG testing for population-level trend monitoring is supported.
Wei-Ya Mao, Meng Yuan, Zhao-Yang Fang et al.· Frontiers in Immunology· 0 citations
Gastric cancer remains a major cause of cancer-related mortality worldwide, largely due to late diagnosis and pronounced molecular heterogeneity. Although genomic and transcriptomic studies have advanced understanding of gastric tumor biology, they do not fully capture dynamic changes in protein expression, post-transl...
Pan-Ning Wang, Yu-Lin Xiao, Shu-Hong Luo et al.· Frontiers in Oncology· 0 citations
Aging is a progressive, multisystem process characterized by declining physiological resilience and increased susceptibility to chronic diseases. Recent advances in high-throughput proteomics have enabled comprehensive mapping of age-related changes across circulating proteins, revealing dynamic and non-linear trajecto...
Ying Luo, Yu-Lin Xiao, Jie-Hua Chen et al.· Frontiers in Aging· 0 citations
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