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Review Open access Sep 2026

PRDM16 as a Multifaceted Pharmacological Target in Kidney Diseases: From Epigenetic Mechanisms to Therapeutic Strategies

PRDM16 is a PR domain-containing epigenetic regulator with intrinsic histone methyltransferase activity and scaffolding interactions with corepressor complexes such as CtBP1/2. Beyond its well-established roles in adipose biology, emerging evidence positions PRDM16 as a central node linking chromatin regulation, metabo...

Qiu-Yu Dai, Shu Rong · 0 citations

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