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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

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Shu-Ya Chang

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Open access Sep 2026

Tumor-associated osteoclasts converge on a matrix-sulfation program across human bone tumors

Introduction Osteoclasts mediate the bone destruction that drives much of the morbidity of giant-cell tumor of bone, osteosarcoma, and skeletal metastasis, yet these large multinucleated cells are lost in droplet single-cell data and have never been defined as a disease cell state. Methods We reanalyzed 378,936 cells f...

Meng-Yuan Lei, Shu-Ya Chang, Ning-Jing Lei et al. · 0 citations
Open access Sep 2026

In vivo CRISPR Screening Reveals LBR as a Regulator of CD8+ T Cell Fate Decision.

CD8+ T cells play an important role in anti-infection and anti-tumor immunity. Metabolic reprogramming has emerged as a critical regulator of T cell function, yet the roles of specific cholesterol-associated proteins during T cell fate trajectories remain unclear. Here, using an in vivo CRISPR screen in CD8+ T cells du...

Qi-Ying Zhang, Shu-Ya Chang, Sheng-Li Zhao et al. · 0 citations

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