Shu-Ying Wang

Isoleucine102 and tryptophan104 of the Staphylococcus aureus formyl peptide receptor-like 1 inhibitor (FLIPr) are critical for mouse Fcγ receptor binding and inhibition of neutrophil phagocytosis.

Staphylococcus aureus employs a diverse repertoire of immune evasion proteins to escape host defenses. Formyl peptide receptor-like 1 inhibitory protein (FLIPr) is a secreted staphylococcal factor that targets both chemoattractant receptors and Fc gamma receptors (FcγRs) to suppress leukocyte activation and antibody-de...