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Review Open access Sep 2026

P2X7 Receptor in Rare Diseases: Shared Molecular Mechanisms and Therapeutic Implications

Abstract Rare diseases (RDs) are individually uncommon but collectively affect a large global population, and the vast majority still lack effective disease-modifying therapies. With advances in genomics and data-sharing platforms, research has increasingly shifted from a single-disease perspective to the search for co...

Xin-Yi Xiao, G. Cao, Shuai Hou et al. · 0 citations
Review Open access Sep 2026

The Efficacy of Different Exercise Intervention Models and Dosages on Post-Stroke Depression: A Systematic Review and Network Meta-Analysis.

AIMS/BACKGROUND Post-stroke depression (PSD) is a prevalent psychological complication among stroke survivors. Exercise intervention, as a non-pharmacological therapeutic approach, plays a crucial role in the rehabilitation of PSD. This study aimed to systematically evaluate the efficacy of various exercise interventio...

Xiao-Lu Fan, Xin-Yu Dai, Quan-Cheng Peng et al. · 0 citations
Open access Sep 2026

Distinct and Shared Brain-Wide Activation Patterns in Mouse Models of Inflammatory and Neuropathic Pain

Objective Inflammatory and neuropathic pain arise from different peripheral insults but share nociceptive and affective features. Whether they recruit common or model-specific brain-wide activation patterns remains unclear. We compared regional neuronal activation and interregional co-activation in mouse models of thes...

Shuai Hou, Rui-Zhu Zhou, Liu-Xuan He et al. · 0 citations

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