Shuai-Shuai Gong

Ruscogenin attenuates sepsis-induced multiple organ injury by inhibiting NMMHC IIA.

Sepsis-induced endothelial dysfunction contributes to systemic inflammation and multiple organ injury. Non-muscle myosin heavy chain IIA (NMMHC IIA) has emerged as a potential therapeutic target for sepsis. However, effective interventions remain limited. This study investigated whether ruscogenin (RUS) alleviates seps...