Bioinformatics analysis of the alterations in neuregulin 1/4 and their correlation with ferroptosis-related genes in amyotrophic lateral sclerosis
Background & Objective: Dysregulation of the ErbB4 signaling pathway has been implicated as a significant factor in the pathogenesis of amyotrophic lateral sclerosis (ALS), with neuregulin 1 (NRG1) and NRG4 serving as key regulatory ligands of ErbB4. This study mainly employs bioinformatics approaches to investigate...