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Author

Shuang Jia

3 papers indexed here

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Review Open access Sep 2026

Engineering TnpB as a compact RNA-guided genome editor from molecular constraints to design principles

Recent discoveries of non-CRISPR RNA-guided nucleases have expanded the landscape of programmable genome editing beyond canonical Cas systems. Among these, TnpB proteins derived from IS200/IS605-family transposable elements are ultra-compact RNA-guided DNA endonucleases with potential for delivery-constrained genome en...

Bin Ma, Yi-Miao Li, Dong-Sheng Zhang et al. · 0 citations
Open access Sep 2026

A native single-transcript TnpB architecture enables efficient virus-induced genome editing and visual screening of heritable progeny harboring phenotypically silent edits

This ultra-compact design enables simultaneous packaging of the editing system and an NbPDS silencing module into a single TRV vector, achieving robust editing in systemic Nicotiana benthamiana tissues and establishing a dual VIGE-VIGS strategy for direct visual selection of heritable, transgene-free edited progeny via...

Rui Wang, Hong-Fei Liu, Shuang Jia et al. · 0 citations
Open access Aug 2026

Application of a Bioactive Compound 2,4-Di-tert-butylphenol in Nanoemulsion Form for Shelf-Life Extension of Cherry Tomatoes: From Microbial Inactivation to Quality and Safety Evaluation

Postharvest spoilage of cherry tomatoes caused by pathogenic microorganisms and oxidative browning leads to significant economic losses and food waste. Natural bioactive compounds are gaining increasing attention as alternatives to synthetic pesticides. In this study, a nanoemulsion (NED) formulation of nature-derived...

Yan-Xin Zhang, Hui Li, Chenxvan Yan et al. · 0 citations

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