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Author

Shuang Wu

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2 papers indexed here

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Review Aug 2026

PHGDH: metabolic enzyme or signaling hub? From broad-spectrum inhibition toward context-adapted therapeutic targeting.

Phosphoglycerate dehydrogenase (PHGDH), the rate-limiting enzyme of the de novo serine synthesis pathway (SSP), has emerged as a context-dependent metabolic hub that integrates glycolysis, one-carbon metabolism, redox homeostasis, and epigenetic regulation. It is regulated by a multi-layered network encompassing transc...

Cui-Cui Sun, Shuang Wu, Zihan Li et al. · 0 citations
Review Aug 2026

The regulatory role of non-coding RNAs in taxane resistance of breast cancer.

Targeting ncRNAs via various therapeutic approaches, including herbal compounds and synthetic peptides, has shown hopeful findings in reversing taxane resistance in breast cancer, highlighting a promising avenue for the management of taxane resistance in breast cancer.

Cui-Cui Sun, Lingling Lv, Qinzheng Xu et al. · 0 citations

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