Computed Tomography-Derived Sarcopenia and Two- Versus Three-Dimensional Body Composition for Prognostication in Colorectal Cancer Patients Receiving Chemoradiotherapy: An Automated Deep Learning Segmentation Study with External Reproducibility Assessment
Background: Skeletal muscle depletion predicts poor outcomes in gastrointestinal cancers, but whether volumetric three-dimensional (3D) body composition adds anything over the standard two-dimensional (2D) single-slice approach in colorectal cancer (CRC) patients receiving chemoradiotherapy is unclear. We quantified CT...