Shubha Das

HumanToxPredict: An interpretable data-driven framework for human oral TDLo prediction and toxicity assessment of pharmaceuticals and bioactive compounds.

Predicting the human toxic dose low (TDLo) is critically important for pharmaceutical safety assessment and regulatory toxicology. A global computational toxicology framework that integrates toxicity data for children, infants, men, and women was developed using indicator-variable-based demographic encoding. Initially,...