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Author

Shufang Ye

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Open access Aug 2026

TMEM189/PEDS1 deficiency aggravates MASH progression by promoting FASN-mediated macrophage activation

Transmembrane protein 189 (TMEM189), also known as plasmanylethanolamine desaturase 1 (PEDS1), is involved in plasmalogen biosynthesis, phospholipid metabolism, ferroptosis, and autophagy. However, whether TMEM189/PEDS1 regulates macrophages and disease-related inflammatory responses remains unclear. Here, we for t...

Pengli Guo, Jinqiu Feng, Yaxin Lou et al. · 0 citations

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