Author

Shujun Lin

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Aug 2026

Single-cell reanalysis characterizes an Osmr+ astrocyte state and predicts midkine signaling to Cox6b1+ glutamatergic neurons at 24 h after traumatic brain injury.

BACKGROUND Traumatic brain injury (TBI) remains a leading cause of mortality and long-term neurological disability worldwide. The cellular heterogeneity and intercellular communication in the injured brain remain incompletely defined, particularly the astrocyte-neuron crosstalk that could drive potential interventions....

Fu Zhao, Lu-Xi Cao, Jia-Nan Chen et al. · Brain Research · 0 citations

Open access Aug 2026

Electroacupuncture Prevents TBI-Induced Synaptic Loss by Inhibiting CaMKII/Drp1-Dependent Mitochondrial Fission

(1) Background: Traumatic brain injury (TBI) triggers synaptic loss, leading to long-term neurological deficits. Electroacupuncture (EA) benefits neurological conditions, but its mechanisms after TBI remain unclear. (2) Methods: We used a controlled cortical impact (CCI) mouse model. Behavioral outcomes were assessed u...

Si-Si Zhao, Lu-Xi Cao, Feidan Deng et al. · Biomolecules · 1 citation

Shujun Lin

Single-cell reanalysis characterizes an Osmr+ astrocyte state and predicts midkine signaling to Cox6b1+ glutamatergic neurons at 24 h after traumatic brain injury.

Electroacupuncture Prevents TBI-Induced Synaptic Loss by Inhibiting CaMKII/Drp1-Dependent Mitochondrial Fission

Single-cell reanalysis characterizes an Osmr+ astrocyte state and predicts midkine signaling to Cox6b1+ glutamatergic neurons at 24 h after traumatic brain injury.