Summary Idiopathic hyperaldosteronism (IHA) is a significant cause of secondary hypertension. Emerging evidence links the gut microbiota to endocrine and cardiovascular diseases. We integrated human genetics, multi-omics, and fecal microbiota transplantation (FMT) to investigate the association between IHA and gut micr...
Yuanliang Jiang, Qing-Liang Zeng, Lin-Qiang Ma et al.· iScience· 0 citations
Guidelines suggest that the risk of mortality in diabetic foot disease (DFD) is comparable to that of cancer; however, high‐quality evidence is lacking. We aimed to compare the mortality of DFD with that of various cancers based on data from international cohorts.
Comprehensive proteomic profiling of adrenal cortisol-producing adenomas reveals a central role for cholesterol metabolic reprogramming in the pathogenesis of CPAs and downregulation of calcium binding protein 39 like (CAB39L) is uncovered as a key driver of pathological cortisol production.
Xuyang Shi, Yi Yang, Chunxue He et al.· Metabolism: Clinical and Exp...· 0 citations
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