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Author

Shun-Jie Zhang

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Open access Oct 2026

Disease-associated NK-cell state remodeling reveals transcriptional profiles predictive of clinical phenotypes

Natural killer (NK) cells adapt their cellular states to diverse tissue and inflammatory environments, yet how this plasticity manifests across pathological contexts and relates to patient-level disease phenotypes remains poorly defined. Here we established the Human NK-cell Atlas (HNKA) from over 1 million NK cells, i...

F. Meng, Pei-Ran Lin, Shun-Jie Zhang et al. · 0 citations
Open access Sep 2026

Social disconnection integrates genetic and proteomic risks in suicidal ideation and depression

Suicidal ideation (SI) and major depressive disorder (MDD) are complex psychiatric conditions arising from the interplay of genetic liability, molecular processes, and psychosocial factors. While these dimensions have been extensively studied in isolation, their joint contribution to SI and MDD remains unclear. This st...

Si-Hong Li, Zhong-Ting Huang, Hui Chen et al. · 0 citations

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