Shun-Xin Han

Targeting PGAM1 Y119 Phosphorylation Resensitizes Non-Small Cell Lung Cancer to Cisplatin Therapy by Promoting Oxidative Stress and DNA Damage.

Cisplatin resistance remains a primary challenge in the clinical management of non-small cell lung cancer (NSCLC), yet the regulatory targets underlying this resistance remain largely unknown. It is well established that cisplatin kills tumor cells through the induction of DNA damage and the accumulation of reactive ox...