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Open access Sep 2026

Senescent fibroblasts as drivers of malignant progression in gastric cancer.

Cancer-associated fibroblasts (CAFs) are key components of the tumor microenvironment and contribute substantially to gastric cancer progression. However, the phenotypic and functional heterogeneity of CAFs in gastric cancer remains incompletely characterized. Here, we analyzed single-cell transcriptomic data from gast...

Yu-Sheng Luo, L. Zhong, Ke-An Mu et al. · 0 citations
Open access Aug 2026

CSNK2B Expression Aligns with a GDF15-Associated Immune Molecular State in Hepatocellular Carcinoma

Background: Hepatocellular carcinoma (HCC) remains a major cause of cancer-related mortality, and responses to immune checkpoint blockade are often limited. Casein kinase 2 beta (CK2beta), encoded by CSNK2B, has established tumor-intrinsic functions, but its relationship with immune states in HCC remains unclear. Metho...

Hui-Ru Dai, Ya-Jie Li, Jun-Jie Zhang et al. · 0 citations

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